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Bile acids inhibit duodenal secretin expression via orphan nuclear receptor small heterodimer partner (SHP)

Small heterodimer partner (SHP) is an orphan nuclear receptor in which gene expression can be upregulated by bile acids. It regulates its target genes by repressing the transcriptional activities of other nuclear receptors including NeuroD, which has been shown to regulate secretin gene expression....

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Detalhes bibliográficos
Main Authors: Lam, Ian P. Y., Lee, Leo T. O., Choi, Hueng-Sik, Alpini, Gianfranco, Chow, Billy K. C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2711755/
https://ncbi.nlm.nih.gov/pubmed/19372104
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00094.2009
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