Bile acids inhibit duodenal secretin expression via orphan nuclear receptor small heterodimer partner (SHP)

Small heterodimer partner (SHP) is an orphan nuclear receptor in which gene expression can be upregulated by bile acids. It regulates its target genes by repressing the transcriptional activities of other nuclear receptors including NeuroD, which has been shown to regulate secretin gene expression....

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Bibliografiske detaljer
Main Authors: Lam, Ian P. Y., Lee, Leo T. O., Choi, Hueng-Sik, Alpini, Gianfranco, Chow, Billy K. C.
Format: Artigo
Sprog:Inglês
Udgivet: American Physiological Society 2009
Fag:
Liver and Biliary Tract
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2711755/
https://ncbi.nlm.nih.gov/pubmed/19372104
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00094.2009
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