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Arginine Methylation by PRMT5 at a Naturally Occurring Mutation Site Is Critical for Liver Metabolic Regulation by Small Heterodimer Partner

Small Heterodimer Partner (SHP) inhibits numerous transcription factors that are involved in diverse biological processes, including lipid and glucose metabolism. In response to increased hepatic bile acids, SHP gene expression is induced and the SHP protein is stabilized. We now show that the activ...

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Detalhes bibliográficos
Main Authors: Kanamaluru, Deepthi, Xiao, Zhen, Fang, Sungsoon, Choi, Sung-E, Kim, Dong-Hyun, Veenstra, Timothy D., Kemper, Jongsook Kim
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3135303/
https://ncbi.nlm.nih.gov/pubmed/21262773
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01212-10
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