Suppression of Sproutys Has a Therapeutic Effect for a Mouse Model of Ischemia by Enhancing Angiogenesis

Sprouty proteins (Sproutys) inhibit receptor tyrosine kinase signaling and control various aspects of branching morphogenesis. In this study, we examined the physiological function of Sproutys in angiogenesis, using gene targeting and short-hairpin RNA (shRNA) knockdown strategies. Sprouty2 and Spro...

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Bibliografiska uppgifter
Huvudupphovsmän: Taniguchi, Koji, Sasaki, Ken-ichiro, Watari, Kousuke, Yasukawa, Hideo, Imaizumi, Tsutomu, Ayada, Toranoshin, Okamoto, Fuyuki, Ishizaki, Takuma, Kato, Reiko, Kohno, Ri-ichiro, Kimura, Hiroshi, Sato, Yasufumi, Ono, Mayumi, Yonemitsu, Yoshikazu, Yoshimura, Akihiko
Materialtyp: Artigo
Språk:Inglês
Publicerad: Public Library of Science 2009
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2674940/
https://ncbi.nlm.nih.gov/pubmed/19424491
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0005467
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