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The Sprouty/Spred family as tumor suppressors: Coming of age

The Ras/Raf/ERK pathway is one of the most frequently dysregulated signaling pathways in various cancers. In some such cancers, Ras and Raf are hotspots for mutations, which cause continuous activation of this pathway. However, in some other cancers, it is known that negative regulators of the Ras/R...

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Detalhes bibliográficos
Publicado no:Cancer Sci
Main Authors: Kawazoe, Tetsuro, Taniguchi, Koji
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6501019/
https://ncbi.nlm.nih.gov/pubmed/30874331
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.13999
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