Suppression of Sproutys Has a Therapeutic Effect for a Mouse Model of Ischemia by Enhancing Angiogenesis

Sprouty proteins (Sproutys) inhibit receptor tyrosine kinase signaling and control various aspects of branching morphogenesis. In this study, we examined the physiological function of Sproutys in angiogenesis, using gene targeting and short-hairpin RNA (shRNA) knockdown strategies. Sprouty2 and Spro...

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Detalhes bibliográficos
Main Authors: Taniguchi, Koji, Sasaki, Ken-ichiro, Watari, Kousuke, Yasukawa, Hideo, Imaizumi, Tsutomu, Ayada, Toranoshin, Okamoto, Fuyuki, Ishizaki, Takuma, Kato, Reiko, Kohno, Ri-ichiro, Kimura, Hiroshi, Sato, Yasufumi, Ono, Mayumi, Yonemitsu, Yoshikazu, Yoshimura, Akihiko
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2009
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2674940/
https://ncbi.nlm.nih.gov/pubmed/19424491
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0005467
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