Suppression of Sproutys Has a Therapeutic Effect for a Mouse Model of Ischemia by Enhancing Angiogenesis

Sprouty proteins (Sproutys) inhibit receptor tyrosine kinase signaling and control various aspects of branching morphogenesis. In this study, we examined the physiological function of Sproutys in angiogenesis, using gene targeting and short-hairpin RNA (shRNA) knockdown strategies. Sprouty2 and Spro...

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Bibliografische gegevens
Hoofdauteurs: Taniguchi, Koji, Sasaki, Ken-ichiro, Watari, Kousuke, Yasukawa, Hideo, Imaizumi, Tsutomu, Ayada, Toranoshin, Okamoto, Fuyuki, Ishizaki, Takuma, Kato, Reiko, Kohno, Ri-ichiro, Kimura, Hiroshi, Sato, Yasufumi, Ono, Mayumi, Yonemitsu, Yoshikazu, Yoshimura, Akihiko
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2009
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Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2674940/
https://ncbi.nlm.nih.gov/pubmed/19424491
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0005467
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