Suppression of Sproutys Has a Therapeutic Effect for a Mouse Model of Ischemia by Enhancing Angiogenesis

Sprouty proteins (Sproutys) inhibit receptor tyrosine kinase signaling and control various aspects of branching morphogenesis. In this study, we examined the physiological function of Sproutys in angiogenesis, using gene targeting and short-hairpin RNA (shRNA) knockdown strategies. Sprouty2 and Spro...

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Main Authors: Taniguchi, Koji, Sasaki, Ken-ichiro, Watari, Kousuke, Yasukawa, Hideo, Imaizumi, Tsutomu, Ayada, Toranoshin, Okamoto, Fuyuki, Ishizaki, Takuma, Kato, Reiko, Kohno, Ri-ichiro, Kimura, Hiroshi, Sato, Yasufumi, Ono, Mayumi, Yonemitsu, Yoshikazu, Yoshimura, Akihiko
格式: Artigo
語言:Inglês
出版: Public Library of Science 2009
主題:
Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2674940/
https://ncbi.nlm.nih.gov/pubmed/19424491
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0005467
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