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Spreds Are Essential for Embryonic Lymphangiogenesis by Regulating Vascular Endothelial Growth Factor Receptor 3 Signaling

Spred/Sprouty family proteins negatively regulate growth factor-induced ERK activation. Although the individual physiological roles of Spred-1 and Spred-2 have been investigated using gene-disrupted mice, the overlapping functions of Spred-1 and Spred-2 have not been clarified. Here, we demonstrate...

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Main Authors: Taniguchi, Koji, Kohno, Ri-ichiro, Ayada, Toranoshin, Kato, Reiko, Ichiyama, Kenji, Morisada, Tohru, Oike, Yuichi, Yonemitsu, Yoshikazu, Maehara, Yoshihiko, Yoshimura, Akihiko
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2007
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1900061/
https://ncbi.nlm.nih.gov/pubmed/17438136
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01600-06
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