Spred-1 negatively regulates allergen-induced airway eosinophilia and hyperresponsiveness

T helper 2 cytokines, including interleukin (IL)-4, IL-5, and IL-13, play a critical role in allergic asthma. These cytokines transmit signals through the Janus kinase/signal transducer and activator of transcription (STAT) and the Ras–extracellular signal-regulated kinase (ERK) signaling pathways....

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Bibliographic Details
Main Authors: Inoue, Hiromasa, Kato, Reiko, Fukuyama, Satoru, Nonami, Atsushi, Taniguchi, Kouji, Matsumoto, Koichiro, Nakano, Takako, Tsuda, Miyuki, Matsumura, Mikiko, Kubo, Masato, Ishikawa, Fumihiko, Moon, Byoung-gon, Takatsu, Kiyoshi, Nakanishi, Yoichi, Yoshimura, Akihiko
Format: Artigo
Language:Inglês
Published: The Rockefeller University Press 2005
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2212755/
https://ncbi.nlm.nih.gov/pubmed/15630138
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20040616
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