Small interfering RNA against CD86 during allergen challenge blocks experimental allergic asthma

BACKGROUND: CD86-CD28 interaction has been suggested as the principal costimulatory pathway for the activation and differentiation of naïve T cells in allergic inflammation. However, it remains uncertain whether this pathway also has an essential role in the effector phase. We sought to determine th...

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Detalhes bibliográficos
Publicado no:Respir Res
Main Authors: Asai-Tajiri, Yukari, Matsumoto, Koichiro, Fukuyama, Satoru, Kan-o, Keiko, Nakano, Takako, Tonai, Ken, Ohno, Tatsukuni, Azuma, Miyuki, Inoue, Hiromasa, Nakanishi, Yoichi
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4216659/
https://ncbi.nlm.nih.gov/pubmed/25344652
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12931-014-0132-z
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