Spred-2 Suppresses Aorta-Gonad-Mesonephros Hematopoiesis by Inhibiting MAP Kinase Activation

In midgestation mouse embryos, the aorta-gonad-mesonephros (AGM) region generates hematopoietic stem cells and definitive hematopoiesis is regulated by cell–cell interaction and signaling molecules. We showed that a Ras/mitogen-activated protein (MAP) kinase signaling-specific inhibitor and a domina...

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Detalhes bibliográficos
Main Authors: Nobuhisa, Ikuo, Kato, Reiko, Inoue, Hirofumi, Takizawa, Makiko, Okita, Keisuke, Yoshimura, Akihiko, Taga, Tetsuya
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2004
Assuntos:
Brief Definitive Report
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2213301/
https://ncbi.nlm.nih.gov/pubmed/14981116
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20030830
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