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Loop Tryptophan Human PNP Reveals Submillisecond Protein Dynamics

Human PNP is a homotrimer, containing three non-conserved tryptophan residues at positions 16, 94 and 178, all remote from the catalytic site. The catalytic sites of PNP are located near the subunit-subunit interfaces where residue F159 is a catalytic site residue donated from an adjacent subunit. F...

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Autors principals: Ghanem, Mahmoud, Zhadin, Nickolay, Callender, Robert, Schramm, Vern L.
Format: Artigo
Idioma:Inglês
Publicat: 2009
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2674222/
https://ncbi.nlm.nih.gov/pubmed/19191546
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi802339c
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