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Probing the Role of Dynamics in Hydride Transfer Catalyzed by Lactate Dehydrogenase
The dynamic nature of the interconversion of pyruvate to lactate as catalyzed by lactate dehydrogenase (LDH) is characterized by laser-induced temperature jump relaxation spectroscopy with a resolution of 20 ns. An equilibrium system of LDH·NADH plus pyruvate and LDH·NAD(+) plus lactate is perturbed...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Biophysical Society
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2483756/ https://ncbi.nlm.nih.gov/pubmed/18487309 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.108.132464 |
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