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Investigation of Catalytic Loop Structure, Dynamics and Function Relationship of Yersinia Protein Tyrosine Phosphatase by Temperature-Jump Relaxation Spectroscopy and X-ray Structural Determination
Yersinia Protein Tyrosine Phosphatase (YopH) is the most efficient enzyme amongst all PTPases and YopH is hyperactive compared to human PTPases, interferes with mammalian cellular pathways to achieve the pathogenicity of Yersinia. Two properties related to the catalytic loop structure differences ha...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3380360/ https://ncbi.nlm.nih.gov/pubmed/22564106 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jp3037846 |
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