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Computational Studies of Catalytic Loop Dynamics in Yersinia Protein Tyrosine Phosphatase Using Pathway Optimization Methods
Yersinia Protein Tyrosine Phosphatase (YopH) is the most efficient enzyme amongst all known PTPases and relies on its catalytic loop movements for substrate binding and catalysis. Fluorescence, NMR and UV resonance Raman (UVRR) techniques have been used to study the thermodynamic and dynamic propert...
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| Publicado en: | J Phys Chem B |
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| Autores principales: | , , , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2019
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6752976/ https://ncbi.nlm.nih.gov/pubmed/31437399 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jpcb.9b06759 |
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