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SUR1: a unique ATP-binding cassette protein that functions as an ion channel regulator
SUR1 is an ATP-binding cassette (ABC) transporter with a novel function. In contrast to other ABC proteins, it serves as the regulatory subunit of an ion channel. The ATP-sensitive (K(ATP)) channel is an octameric complex of four pore-forming Kir6.2 subunits and four regulatory SUR1 subunits, and it...
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Hauptverfasser: | , , , , , |
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Format: | Artigo |
Sprache: | Inglês |
Veröffentlicht: |
The Royal Society
2008
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Schlagworte: | |
Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2674095/ https://ncbi.nlm.nih.gov/pubmed/18990670 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rstb.2008.0142 |
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