Essential Role of DAP12 Signaling in Macrophage Programming into a Fusion-Competent State

Multinucleated giant cells, formed by fusion of macrophages, are a hallmark of granulomatous inflammation. With a genetic approach, we show that signaling through the adaptor protein DAP12 (DNAX activating protein of 12 kD), its associated receptor triggering receptor expressed by myeloid cells 2 (T...

Descrición completa

Gardado en:
Detalles Bibliográficos
Main Authors: Helming, Laura, Tomasello, Elena, Kyriakides, Themis R., Martinez, Fernando O., Takai, Toshiyuki, Gordon, Siamon, Vivier, Eric
Formato: Artigo
Idioma:Inglês
Publicado: 2008
Assuntos:
Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2673960/
https://ncbi.nlm.nih.gov/pubmed/18957693
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.1159665
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!

Títulos similares