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Macrophage colony stimulating factor induces macrophage proliferation and survival through a pathway involving DAP12 and β-catenin

Macrophage colony stimulating factor (MCSF) influences proliferation and survival of mononuclear phagocytes through the CSF-1 receptor. The DAP12 adaptor protein, which transduces signals emanating from various myeloid receptors, is critical for mononuclear phagocyte function. DAP12-mutant mice and...

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Detalhes bibliográficos
Main Authors: Otero, Karel, Turnbull, Isaiah R, Poliani, Pietro Luigi, Vermi, William, Cerutti, Elisa, Aoshi, Taiki, Tassi, Ilaria, Takai, Toshiyuki, Stanley, Samuel L., Miller, Mark, Shaw, Andrey S., Colonna, Marco
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4004764/
https://ncbi.nlm.nih.gov/pubmed/19503107
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ni.1744
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