Signal adaptor DAP10 associates with MDL-1 and triggers osteoclastogenesis in cooperation with DAP12

Osteoclasts, cells of myeloid lineage, play a unique role in bone resorption, maintaining skeletal homeostasis in concert with bone-producing osteoblasts. Osteoclast development and maturation (osteoclastogenesis) is driven by receptor activator of NF-κB ligand and macrophage-colony stimulating fact...

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Hlavní autoři: Inui, Masanori, Kikuchi, Yuki, Aoki, Naoko, Endo, Shota, Maeda, Tsutomu, Sugahara-Tobinai, Akiko, Fujimura, Shion, Nakamura, Akira, Kumanogoh, Atsushi, Colonna, Marco, Takai, Toshiyuki
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2009
Témata:
Biological Sciences
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2660769/
https://ncbi.nlm.nih.gov/pubmed/19251634
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0900463106
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