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The scavenger receptor CD36 plays a role in cytokine-induced macrophage fusion

Multinucleated giant cells, characteristic of granulomatous infections, originate from the fusion of macrophages. Using an antibody screening strategy we found that the scavenger receptor CD36 participates in macrophage fusion induced by the cytokines IL-4 and GM-CSF. Our results demonstrate that ex...

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Библиографические подробности
Главные авторы: Helming, Laura, Winter, Julia, Gordon, Siamon
Формат: Artigo
Язык:Inglês
Опубликовано: Company of Biologists 2009
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2714432/
https://ncbi.nlm.nih.gov/pubmed/19155290
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.037200
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