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The scavenger receptor CD36 plays a role in cytokine-induced macrophage fusion

Multinucleated giant cells, characteristic of granulomatous infections, originate from the fusion of macrophages. Using an antibody screening strategy we found that the scavenger receptor CD36 participates in macrophage fusion induced by the cytokines IL-4 and GM-CSF. Our results demonstrate that ex...

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Detalhes bibliográficos
Main Authors: Helming, Laura, Winter, Julia, Gordon, Siamon
Formato: Artigo
Idioma:Inglês
Publicado em: Company of Biologists 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2714432/
https://ncbi.nlm.nih.gov/pubmed/19155290
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.037200
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