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Sulfation of chondroitin sulfate proteoglycans is necessary for proper Indian hedgehog signaling in the developing growth plate

In contrast to the functional role of heparan sulfate proteoglycans (HSPGs), the importance of chondroitin sulfate proteoglycans (CSPGs) in modulating signaling pathways involving hedgehog proteins, wingless-related proteins and fibroblast growth factors remains unclear. To elucidate the importance...

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Detalles Bibliográficos
Main Authors: Cortes, Mauricio, Baria, Alexis T., Schwartz, Nancy B.
Formato: Artigo
Idioma:Inglês
Publicado: Company of Biologists 2009
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2673757/
https://ncbi.nlm.nih.gov/pubmed/19369399
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.030742
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