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Aggrecan is required for growth plate cytoarchitecture and differentiation

The proteoglycan aggrecan is a prominent component of the extracellular matrix in growth plate cartilage. A naturally occurring, recessive, perinatally lethal mutation in the aggrecan core protein gene, cmd(bc) (Acan(cmd-Bc)), that deletes the entire protein-coding sequence provided a model in which...

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Detalhes bibliográficos
Publicado no:Dev Biol
Main Authors: Lauing, Kristen L., Cortes, Mauricio, Domowicz, Miriam S., Henry, Judith G., Baria, Alexis T., Schwartz, Nancy B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4261049/
https://ncbi.nlm.nih.gov/pubmed/25446537
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2014.10.005
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