Sulfation of chondroitin sulfate proteoglycans is necessary for proper Indian hedgehog signaling in the developing growth plate

In contrast to the functional role of heparan sulfate proteoglycans (HSPGs), the importance of chondroitin sulfate proteoglycans (CSPGs) in modulating signaling pathways involving hedgehog proteins, wingless-related proteins and fibroblast growth factors remains unclear. To elucidate the importance...

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Bibliographic Details
Main Authors: Cortes, Mauricio, Baria, Alexis T., Schwartz, Nancy B.
Format: Artigo
Language:Inglês
Published: Company of Biologists 2009
Subjects:
Research Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2673757/
https://ncbi.nlm.nih.gov/pubmed/19369399
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.030742
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