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Sulfation of chondroitin sulfate proteoglycans is necessary for proper Indian hedgehog signaling in the developing growth plate

In contrast to the functional role of heparan sulfate proteoglycans (HSPGs), the importance of chondroitin sulfate proteoglycans (CSPGs) in modulating signaling pathways involving hedgehog proteins, wingless-related proteins and fibroblast growth factors remains unclear. To elucidate the importance...

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Autors principals: Cortes, Mauricio, Baria, Alexis T., Schwartz, Nancy B.
Format: Artigo
Idioma:Inglês
Publicat: Company of Biologists 2009
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2673757/
https://ncbi.nlm.nih.gov/pubmed/19369399
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.030742
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