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Sulfation of chondroitin sulfate proteoglycans is necessary for proper Indian hedgehog signaling in the developing growth plate

In contrast to the functional role of heparan sulfate proteoglycans (HSPGs), the importance of chondroitin sulfate proteoglycans (CSPGs) in modulating signaling pathways involving hedgehog proteins, wingless-related proteins and fibroblast growth factors remains unclear. To elucidate the importance...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Cortes, Mauricio, Baria, Alexis T., Schwartz, Nancy B.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Company of Biologists 2009
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2673757/
https://ncbi.nlm.nih.gov/pubmed/19369399
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.030742
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