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Aggrecan is required for growth plate cytoarchitecture and differentiation
The proteoglycan aggrecan is a prominent component of the extracellular matrix in growth plate cartilage. A naturally occurring, recessive, perinatally lethal mutation in the aggrecan core protein gene, cmd(bc) (Acan(cmd-Bc)), that deletes the entire protein-coding sequence provided a model in which...
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Publicado no: | Dev Biol |
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Main Authors: | , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2014
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4261049/ https://ncbi.nlm.nih.gov/pubmed/25446537 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2014.10.005 |
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