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AGGRECAN MODULATION OF GROWTH PLATE MORPHOGENESIS
Chick and mouse embryos with heritable deficiencies of aggrecan exhibit severe dwarfism and premature death, demonstrating the essential involvement of aggrecan in development. The aggrecan-deficient nanomelic (nm) chick mutant E12 fully formed growth plate (GP) is devoid of matrix and exhibits mark...
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| Hauptverfasser: | , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2009
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2810547/ https://ncbi.nlm.nih.gov/pubmed/19268444 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2009.02.024 |
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