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Acetylcholine-induced activation of M(3) muscarinic receptors stimulates robust matrix metalloproteinase gene expression in human colon cancer cells

Previously, we showed that ACh-induced proliferation of human colon cancer cells is mediated by transactivation of epidermal growth factor (EGF) receptors (EGFRs). In the present study, we elucidate the molecular mechanism underlying this action. ACh-induced proliferation of H508 colon cancer cells,...

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書目詳細資料
Main Authors: Xie, Guofeng, Cheng, Kunrong, Shant, Jasleen, Raufman, Jean-Pierre
格式: Artigo
語言:Inglês
出版: American Physiological Society 2009
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2670666/
https://ncbi.nlm.nih.gov/pubmed/19221016
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.90519.2008
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