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Matrix Metalloproteinase-7-Catalyzed Release of HB-EGF Mediates Deoxycholyltaurine-Induced Proliferation of a Human Colon Cancer Cell Line

Prior evidence indicates that bile acids stimulate colon cancer cell proliferation by muscarinic receptor-induced transactivation of epidermal growth factor receptors (EGFR). To explore further the mechanism underlying this action, we tested the hypothesis that bile acids activate a matrix metallopr...

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Bibliographic Details
Main Authors: Cheng, Kunrong, Xie, Guofeng, Raufman, Jean-Pierre
Format: Artigo
Language:Inglês
Published: 2006
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1852457/
https://ncbi.nlm.nih.gov/pubmed/17222808
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bcp.2006.11.028
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