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Acetylcholine-induced activation of M(3) muscarinic receptors stimulates robust matrix metalloproteinase gene expression in human colon cancer cells

Previously, we showed that ACh-induced proliferation of human colon cancer cells is mediated by transactivation of epidermal growth factor (EGF) receptors (EGFRs). In the present study, we elucidate the molecular mechanism underlying this action. ACh-induced proliferation of H508 colon cancer cells,...

詳細記述

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書誌詳細
主要な著者: Xie, Guofeng, Cheng, Kunrong, Shant, Jasleen, Raufman, Jean-Pierre
フォーマット: Artigo
言語:Inglês
出版事項: American Physiological Society 2009
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2670666/
https://ncbi.nlm.nih.gov/pubmed/19221016
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.90519.2008
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