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Acetylcholine-induced activation of M(3) muscarinic receptors stimulates robust matrix metalloproteinase gene expression in human colon cancer cells

Previously, we showed that ACh-induced proliferation of human colon cancer cells is mediated by transactivation of epidermal growth factor (EGF) receptors (EGFRs). In the present study, we elucidate the molecular mechanism underlying this action. ACh-induced proliferation of H508 colon cancer cells,...

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Hlavní autoři: Xie, Guofeng, Cheng, Kunrong, Shant, Jasleen, Raufman, Jean-Pierre
Médium: Artigo
Jazyk:Inglês
Vydáno: American Physiological Society 2009
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2670666/
https://ncbi.nlm.nih.gov/pubmed/19221016
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.90519.2008
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