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The sigma receptor antagonist BD-1063 decreases ethanol intake and reinforcement in animal models of excessive drinking

Sigma receptors (SigRs) have been implicated in behavioral and appetitive effects of psychostimulants and may also modulate the motivating properties of ethanol. The present study tested the hypothesis that SigRs modulate ethanol reinforcement and contribute to excessive ethanol intake. The effects...

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Detalhes bibliográficos
Main Authors: Sabino, Valentina, Cottone, Pietro, Zhao, Yu, Iyer, Malliga R., Steardo, Luca, Rice, Kenner C., Conti, Bruno, Koob, George F., Zorrilla, Eric P.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2669694/
https://ncbi.nlm.nih.gov/pubmed/18946467
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npp.2008.192
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