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Activation of σ-Receptors Induces Binge-like Drinking in Sardinian Alcohol-Preferring Rats

Sigma (σ) receptors have been implicated in the behavioral and motivational effects of alcohol and psychostimulants. Sigma receptor antagonists reduce the reinforcing effects of alcohol and excessive alcohol intake in both genetic (alcohol-preferring rats) and environmental (chronic alcohol-induced)...

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Detalhes bibliográficos
Main Authors: Sabino, Valentina, Cottone, Pietro, Blasio, Angelo, Iyer, Malliga R, Steardo, Luca, Rice, Kenner C, Conti, Bruno, Koob, George F, Zorrilla, Eric P
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3079320/
https://ncbi.nlm.nih.gov/pubmed/21346735
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npp.2011.5
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