Sigma-1 Receptor Mediates Acquisition of Alcohol Drinking and Seeking behavior in Alcohol-Preferring Rats

Sigma-1 receptor (Sig-1R) has been proposed as a novel therapeutic target for drug and alcohol addiction. We have shown previously that Sig-1R agonists facilitate the reinforcing effects of ethanol and induce binge-like drinking, while Sig-1R antagonists block excessive drinking in both genetic and...

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Detalhes bibliográficos
Publicado no:Behav Brain Res
Main Authors: Blasio, Angelo, Valenza, Marta, Iyer, Malliga R., Rice, Kenner C., Steardo, Luca, Hayashi, T., Cottone, Pietro, Sabino, Valentina
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4424067/
https://ncbi.nlm.nih.gov/pubmed/25848705
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbr.2015.03.065
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