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Antagonism of Sigma-1 receptor blocks heavy alcohol drinking and associated hyperalgesia in male mice
BACKGROUND: Alcohol Use Disorder (AUD) is a complex psychiatric disease characterized by high alcohol intake as well as by hyperkatifeia and hyperalgesia during withdrawal. A role for Sigma-1 Receptors (Sig-1Rs) in the rewarding and reinforcing effects of alcohol has started to emerge in recent year...
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| Publicado no: | Alcohol Clin Exp Res |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8295198/ https://ncbi.nlm.nih.gov/pubmed/34060104 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acer.14635 |
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