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Selective reduction of alcohol drinking in Sardinian alcohol-preferring rats by a sigma-1 receptor antagonist

RATIONALE AND OBJECTIVES: Sigma receptors have been implicated in appetitive effects of psychostimulants and in high levels of ethanol intake. This study tested the hypothesis that the sigma-1 receptor subtype (Sig-1R) may modulate ethanol intake. MATERIAL AND METHODS: The effects of acute and repea...

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Detalhes bibliográficos
Main Authors: Sabino, Valentina, Cottone, Pietro, Zhao, Yu, Steardo, Luca, Koob, George F., Zorrilla, Eric P.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2748837/
https://ncbi.nlm.nih.gov/pubmed/19440699
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00213-009-1548-x
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