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PPARα and PPARγ attenuate HIV-induced dysregulation of tight junction proteins by modulations of matrix metalloproteinase and proteasome activities

The blood-brain barrier (BBB) plays an important role in HIV trafficking into the brain and the development of the central nervous system complications in HIV infection. Tight junctions are the main structural and functional elements that regulate the BBB integrity. Exposure of human brain microvasc...

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Bibliografski detalji
Glavni autori: Huang, Wen, Eum, Sung Yong, András, Ibolya E, Hennig, Bernhard, Toborek, Michal
Format: Artigo
Jezik:Inglês
Izdano: The Federation of American Societies for Experimental Biology 2009
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2669424/
https://ncbi.nlm.nih.gov/pubmed/19141539
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.08-121624
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