PPARα and PPARγ attenuate HIV-induced dysregulation of tight junction proteins by modulations of matrix metalloproteinase and proteasome activities

The blood-brain barrier (BBB) plays an important role in HIV trafficking into the brain and the development of the central nervous system complications in HIV infection. Tight junctions are the main structural and functional elements that regulate the BBB integrity. Exposure of human brain microvasc...

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Hlavní autoři: Huang, Wen, Eum, Sung Yong, András, Ibolya E, Hennig, Bernhard, Toborek, Michal
Médium: Artigo
Jazyk:Inglês
Vydáno: The Federation of American Societies for Experimental Biology 2009
Témata:
Research Communications
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2669424/
https://ncbi.nlm.nih.gov/pubmed/19141539
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.08-121624
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