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Disruption of epithelial barrier by quorum-sensing N-3-(oxododecanoyl)-homoserine lactone is mediated by matrix metalloproteinases

The intestinal epithelium forms a selective barrier maintained by tight junctions (TJs) and separating the luminal environment from the submucosal tissues. N-acylhomoserine lactone (AHL) quorum-sensing molecules produced by gram-negative bacteria in the gut can influence homeostasis of the host inte...

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Bibliographic Details
Main Authors: Eum, Sung Yong, Jaraki, Dima, Bertrand, Luc, András, Ibolya E., Toborek, Michal
Format: Artigo
Language:Inglês
Published: American Physiological Society 2014
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4042118/
https://ncbi.nlm.nih.gov/pubmed/24742991
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00016.2014
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