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PPARα AND PPARγ EFFECTIVELY PROTECT AGAINST HIV-INDUCED INFLAMMATORY RESPONSES IN BRAIN ENDOTHELIAL CELLS
Peroxisome proliferator-activated receptors (PPARs) are nuclear receptors which downregulate inflammatory signaling pathways. Therefore, we hypothesized that alterations of PPAR functions can contribute to HIV-1-induced dysfunction of brain endothelial cells. Indeed, treatment with HIV-1 Tat protein...
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| Main Authors: | , , , , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2008
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2597373/ https://ncbi.nlm.nih.gov/pubmed/18710415 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1471-4159.2008.05626.x |
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