PPARα AND PPARγ EFFECTIVELY PROTECT AGAINST HIV-INDUCED INFLAMMATORY RESPONSES IN BRAIN ENDOTHELIAL CELLS

Peroxisome proliferator-activated receptors (PPARs) are nuclear receptors which downregulate inflammatory signaling pathways. Therefore, we hypothesized that alterations of PPAR functions can contribute to HIV-1-induced dysfunction of brain endothelial cells. Indeed, treatment with HIV-1 Tat protein...

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Detalhes bibliográficos
Main Authors: Huang, Wen, Bae Rha, Geun, Han, Min-Joon, Eum, Sung Yong, András, Ibolya E., Zhong, Yu, Hennig, Bernhard, Toborek, Michal
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2597373/
https://ncbi.nlm.nih.gov/pubmed/18710415
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1471-4159.2008.05626.x
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