HIV-1-INDUCED AMYLOID BETA ACCUMULATION IN BRAIN ENDOTHELIAL CELLS IS ATTENUATED BY SIMVASTATIN

HIV-1-infected brains are characterized by increased amyloid deposition. To study the influence of HIV-1 on amyloid beta (Aβ) homeostasis at the blood-brain barrier (BBB) level, we employed a model of brain microvascular endothelial cells exposed to HIV-1 in the presence or absence of Aβ. HIV-1 mark...

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Autores principales: András, Ibolya E., Eum, Sung Yong, Huang, Wen, Zhong, Yu, Hennig, Bernhard, Toborek, Michal
Formato: Artigo
Lenguaje:Inglês
Publicado: 2009
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2818553/
https://ncbi.nlm.nih.gov/pubmed/19944163
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mcn.2009.11.004
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