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Identificaiton of Shc Src Homology 2 Domain-Binding Peptoid – Peptide Hybrids

A fluorescence anisotropy (FA) competition – based Shc Src homology 2 (SH2) domain-binding was established using the high affinity fluorescein isothiocyanate (FITC)-containing peptide, FITC-NH-(CH(2))(4)-CO-pY-Q-G-L-S-amide (8; K(d) = 0.35 μM). Examination of a series of open – chain bis-alkenylamid...

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Autors principals: Choi, Won Jun, Kim, Sung Eun, Stephen, Andrew G., Weidlich, Iwona, Giubellino, Alessio, Liu, Fa, Worthy, Karen M., Bindu, Lakshman, Fivash, Matthew J., Nicklaus, Marc C., Bottaro, Donald P., Fisher, Robert J., Burke, Terrence R.
Format: Artigo
Idioma:Inglês
Publicat: 2009
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2669314/
https://ncbi.nlm.nih.gov/pubmed/19226165
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm800789h
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