Identificaiton of Shc Src Homology 2 Domain-Binding Peptoid – Peptide Hybrids

A fluorescence anisotropy (FA) competition – based Shc Src homology 2 (SH2) domain-binding was established using the high affinity fluorescein isothiocyanate (FITC)-containing peptide, FITC-NH-(CH(2))(4)-CO-pY-Q-G-L-S-amide (8; K(d) = 0.35 μM). Examination of a series of open – chain bis-alkenylamid...

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Detalhes bibliográficos
Main Authors: Choi, Won Jun, Kim, Sung Eun, Stephen, Andrew G., Weidlich, Iwona, Giubellino, Alessio, Liu, Fa, Worthy, Karen M., Bindu, Lakshman, Fivash, Matthew J., Nicklaus, Marc C., Bottaro, Donald P., Fisher, Robert J., Burke, Terrence R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2669314/
https://ncbi.nlm.nih.gov/pubmed/19226165
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm800789h
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