Identificaiton of Shc Src Homology 2 Domain-Binding Peptoid – Peptide Hybrids

A fluorescence anisotropy (FA) competition – based Shc Src homology 2 (SH2) domain-binding was established using the high affinity fluorescein isothiocyanate (FITC)-containing peptide, FITC-NH-(CH(2))(4)-CO-pY-Q-G-L-S-amide (8; K(d) = 0.35 μM). Examination of a series of open – chain bis-alkenylamid...

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Main Authors: Choi, Won Jun, Kim, Sung Eun, Stephen, Andrew G., Weidlich, Iwona, Giubellino, Alessio, Liu, Fa, Worthy, Karen M., Bindu, Lakshman, Fivash, Matthew J., Nicklaus, Marc C., Bottaro, Donald P., Fisher, Robert J., Burke, Terrence R.
Formato: Artigo
Idioma:Inglês
Publicado: 2009
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2669314/
https://ncbi.nlm.nih.gov/pubmed/19226165
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm800789h
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