Identificaiton of Shc Src Homology 2 Domain-Binding Peptoid – Peptide Hybrids

A fluorescence anisotropy (FA) competition – based Shc Src homology 2 (SH2) domain-binding was established using the high affinity fluorescein isothiocyanate (FITC)-containing peptide, FITC-NH-(CH(2))(4)-CO-pY-Q-G-L-S-amide (8; K(d) = 0.35 μM). Examination of a series of open – chain bis-alkenylamid...

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Autori principali: Choi, Won Jun, Kim, Sung Eun, Stephen, Andrew G., Weidlich, Iwona, Giubellino, Alessio, Liu, Fa, Worthy, Karen M., Bindu, Lakshman, Fivash, Matthew J., Nicklaus, Marc C., Bottaro, Donald P., Fisher, Robert J., Burke, Terrence R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2009
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2669314/
https://ncbi.nlm.nih.gov/pubmed/19226165
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm800789h
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