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Transforming Growth Factor β Depletion Is the Primary Determinant of Smad Signaling Kinetics
A cell's decision to growth arrest, apoptose, or differentiate in response to transforming growth factor β (TGF-β) superfamily ligands depends on the ligand concentration. How cells sense the concentration of extracellular bioavailable TGF-β remains poorly understood. We therefore undertook a s...
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| Autores principales: | , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
American Society for Microbiology (ASM)
2009
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2668365/ https://ncbi.nlm.nih.gov/pubmed/19223462 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01443-08 |
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