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Decoding the quantitative nature of TGF-β/Smad signaling

How transforming growth factor-β (TGF-β) signaling elicits diverse cell responses remains elusive, despite the major molecular components of the pathway being known. We contend that understanding TGF-β biology requires mathematical models to decipher the quantitative nature of TGF-β/Smad signaling a...

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Main Authors: Clarke, David C., Liu, Xuedong
格式: Artigo
語言:Inglês
出版: 2008
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2774497/
https://ncbi.nlm.nih.gov/pubmed/18706811
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tcb.2008.06.006
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