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Association of v-ErbA with Smad4 Disrupts TGF-β Signaling
Disruption of the transforming growth factor-β (TGF-β) pathway is observed in the majority of cancers. To further understand TGF-β pathway inactivation in cancer, we stably expressed the v-ErbA oncoprotein in TGF-β responsive cells. v-ErbA participates in erythroleukemic transformation of cells indu...
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| Главные авторы: | , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
The American Society for Cell Biology
2009
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2649266/ https://ncbi.nlm.nih.gov/pubmed/19144825 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E08-08-0836 |
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