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Transforming growth factor-β and breast cancer: Transforming growth factor-β/SMAD signaling defects and cancer
Transforming growth factor-β (TGF-β) is a tumor suppressor, the function of which is compromised in many types of human cancer, including breast cancer. The tumor suppressive effects of TGF-β are caused by potent inhibition of cell proliferation due to cell cycle arrest in the G1 phase. Such antipro...
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| Главный автор: | |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
BioMed Central
2000
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC139432/ https://ncbi.nlm.nih.gov/pubmed/11250700 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/bcr42 |
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