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Transforming growth factor-β and breast cancer: Transforming growth factor-β/SMAD signaling defects and cancer

Transforming growth factor-β (TGF-β) is a tumor suppressor, the function of which is compromised in many types of human cancer, including breast cancer. The tumor suppressive effects of TGF-β are caused by potent inhibition of cell proliferation due to cell cycle arrest in the G1 phase. Such antipro...

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Bibliografiske detaljer
Udgivet i:Breast Cancer Res
Hovedforfatter: Kretzschmar, Marcus
Format: Artigo
Sprog:Inglês
Udgivet: BMC 2000
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC139432/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11250700/
https://ncbi.nlm.nih.govhttps://doi.org/10.1186/bcr42
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