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A Structural Model of the Pore-Forming Region of the Skeletal Muscle Ryanodine Receptor (RyR1)

Ryanodine receptors (RyRs) are ion channels that regulate muscle contraction by releasing calcium ions from intracellular stores into the cytoplasm. Mutations in skeletal muscle RyR (RyR1) give rise to congenital diseases such as central core disease. The absence of high-resolution structures of RyR...

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Bibliografische gegevens
Hoofdauteurs: Ramachandran, Srinivas, Serohijos, Adrian W. R., Xu, Le, Meissner, Gerhard, Dokholyan, Nikolay V.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2009
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2668181/
https://ncbi.nlm.nih.gov/pubmed/19390614
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1000367
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