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Homocysteine effects classical pathway of GPCR down regulation: Gα(q/11), Gα(12/13), G(i/o)
G protein-coupled receptors (GPCRs) are known to modulate intracellular effectors involved in cardiac function. We recently reported homocysteine (Hcy)-induced ERK-phosphorylation was suppressed by pertussis toxin (PTX), which suggested the involvement of GPCRs in initiating signal transduction. An...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2667933/ https://ncbi.nlm.nih.gov/pubmed/18777088 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11010-008-9904-4 |
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